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br Materials and Methods br Author Contributions
2024-05-18
Materials and Methods Author Contributions Conflicts of Interest Acknowledgments This study was funded by the NIH Common Fund (UH2TR000943) through the Office of Strategic Coordination/Office of the NIH Director, an NCI/NIH grant (1R21CA199050), the MD Anderson Cancer Center support gran
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br Conclusion br List of abbreviations br Acknowledgment The
2024-05-18
Conclusion List of abbreviations Acknowledgment The studies performed by our laboratory and presented in this review were supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan, (KAKENHI 17590618 [to H.I.] and KAKENHI 22249017 [to Y.Y.]), and the Japanese S
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Previously using a P lacZ reporter
2024-05-18
Previously, using a P-lacZ reporter gene system, it has been shown that the β-galactosidase activity was 9-fold higher in the stationary phase a66 when compared with those of the exponential phase [15]. Furthermore, inositol supplementation did not have a major effect on the expression of β-galacto
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Acl converts cytosolic citrate CoA and ATP
2024-05-18
Acl converts cytosolic citrate, CoA and ATP into acetyl-CoA, ADP+Pi and oxaloacetate (Fig. 1). This cytosolic enzyme is present in few Prokaryotes and in all Eukaryotes, but not in non-oleaginous yeasts [14]. Thus, this enzyme was presumed to be essential for FA synthesis [1], [13], [15]. In most mi
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Acknowledgments br Introduction Prostate cancer is the first
2024-05-18
Acknowledgments Introduction Prostate cancer is the first leading cause of cancer-related deaths among males in the UK and the second in the US. Despite recent advances in surgery, radiation, medical management and screening, prostate cancer patients suffer high morbidity and mortality and signi
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The presence of crown like
2024-05-18
The presence of crown-like structures and inflammatory factors in the breast of obese patients is associated with considerable changes in intracellular signaling and a profound cellular dysfunction. Secreted pro-inflammatory factors can directly promote breast carcinogenesis as they have been report
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br Materials and methods br Results br Discussion
2024-05-18
Materials and methods Results Discussion Pulmonary fibrosis is a progressive and chronic lung disease and its typical features include vandetanib proliferation, epithelial injury, chronic interstitial inflammation, increased extracellular matrix (ECM) production, and collapse of alveoli, a
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Prolonged duration of antimicrobial agents is also associate
2024-05-17
Prolonged duration of antimicrobial agents is also associated with increased risk of CDI by extending the time disruption of normal enteric flora. This emphasizes the importance for clinicians to adhere to shorter durations of therapy. Although longer durations of therapy are associated with a great
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Anti angiogenic activity of natural products in
2024-05-17
Anti-angiogenic activity of natural products in ocular neovascularization A number of molecules, obtained from the natural source, have been evaluated for ocular neovascularization [14], [15]. As these compounds exhibit antioxidant effects, these were also tried for their therapeutic efficacy in in
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br Identification of the croaker mAR cDNA Testosterone T
2024-05-17
Identification of the croaker mAR cDNA Testosterone (T) was observed to alter steroidogenesis through a nongenomic mechanism (not blocked by the transcription inhibitor, actinomycin D) in Atlantic croaker ovarian tissues (Braun and Thomas, 2003). This action of T was mimicked by T conjugated to B
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Earlier studies with SERMs identified that
2024-05-17
Earlier studies with SERMs identified that distinct chemical scaffolds have the ability to induce unique conformational changes in the ER, resulting in interaction with different cofactor subsets. The same has been demonstrated with SARMs, which induce distinct conformational changes compared to tes
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4SC-202 G has been shown to participate
2024-05-17
Gβγ has been shown to participate in various MT-dependent processes such as cell growth and differentiation [15,[21], [22], [23], [24], [25], [26]]. G-protein β-subunit anti-sense oligonucleotides have been shown to inhibit cell proliferation and cause disorganization of the mitotic spindle in mamma
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It could be hypothesized that the
2024-05-17
It could be hypothesized that the adiponectin system is regulated by gonadal steroid hormones. The lowest concentrations of adiponectin, AdipoR1 and AdipoR2 proteins in the endometrium and myometrium during the mid-luteal and late-luteal phases suggest that progesterone suppresses the expression of
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Streptomycetes are a group of filamentous
2024-05-17
Streptomycetes are a group of filamentous Gram-positive, soil-inhabiting bacteria which have captured enormous screening interest because of their ability to produce and secrete a variety of BMS354825 and extracellular proteins [7]. Among the diverse antibiotics produced by Streptomycetes are the nu
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Targeting the BCR is the ideal strategy
2024-05-17
Targeting the BCR is the ideal strategy to identify the antigen reactive B cells. However, there is concern that B cells could be activated when BCR are bound and cross-linked by antigens, a possibility that is obviously negative for the treatment of autoimmune disease. Proby et al. (2000) tried to
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