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br Introduction Dissociated animal neurons are able
2018-11-09
Introduction Dissociated animal neurons are able to form a neuronal network within a couple of days after being plated on a microelectrode array (MEA) with adequate density [6,10,11]. The developing neuronal network spikes spontaneously. An MEA can trace this spontaneous spiking activity (SSA), w
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Los hacedores de pol tica econ mica del periodo
2018-11-09
Los hacedores de política económica del periodo posguerra, especialmente en la economía estadounidense, que otorgaron una importancia central a la política fiscal, adoptaron un planteamiento diferente, denominado keynesiano. Con A-366 en la propuesta de la Síntesis Neoclásica (Hicks, 1937, Hansen,
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Ramelteon La intermediaci n financiera bancaria en el mbito
2018-11-09
La intermediación financiera bancaria en el ámbito internacional constituye otro aspecto clave para evaluar en qué medida se encuentra amenazada la supremacía del dólar. El cuadro 3 captura, para un conjunto de años seleccionados (2001, 2008 y 2015), la evolución de la participación de las diferente
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br Conformaci n del sector tecnol gico de
2018-11-09
Conformación del sector tecnológico de las baterías Para conceptualizar order UNC0638 la batería o cualquier otra tecnología en un diseño, se puede pensar que la tecnología es una combinación de elementos (N) y conexiones (K) (Potts:2001). Las combinaciones de estos elementos son las conexiones,
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Introduction Geographic factors were also decisive
2018-11-09
Introduction Geographic factors were also decisive for spatial inequality. The continental size and the geographic heterogeneity of the country compounded with very high transport costs to create wide spatial disparities in the levels of productivity and income per capita. (Azzoni and Ferreira, 199
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br Results br Discussion Geography can either limit or
2018-11-09
Results Discussion Geography can either limit or facilitate the spread of infectious diseases, like HIV. The proximity and close cultural ties between populations in Mexico and the southwestern US, have linked these groups for many years. Thus, it is not surprising that in the early days of th
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The low levels of research investment
2018-11-09
The low levels of research investment for syphilis and gonorrhoea remain (Head et al., 2013, 2015b), both in terms of total funding but also when compared to disease burden. Given the increasing levels of purchase GSK126 in strains of Neisseria gonorrhoeae, and the continuing high burden of both the
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br Limitations of existing studies
2018-11-08
Limitations of existing studies and suggestions for future research The incidence of the metabolic disorders including obesity is increasing worldwide and has reached epidemic proportions in developed countries, with notable exceptions of some Southeast Asian countries where seaweeds are part of
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br Results and discussion In order to
2018-11-08
Results and discussion In order to validate our results, we analyzed allelic-specific expression of various genes on the X chromosome. We identified heterozygous single nucleotide polymorphisms (SNPs) located within coding regions of X chromosome genes. We then sequenced the complementary DNA (cD
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There are several limitations to
2018-11-08
There are several limitations to this technology. Fluorescence signals report relative, not absolute, membrane potentials. The temporal response results in loss of high-frequency elements and leads to a small but systematic overestimation of APD. A comparison of ArcLight and the ANEPPS dyes (Herron
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In concert with biochemical cues mechanical
2018-11-08
In concert with biochemical cues, mechanical stimuli can activate or inhibit signaling pathways, and thus regulate transcription factor expression to drive myocardial differentiation, specification, and maturation (Van Vliet et al., 2012; Happe and Engler, 2016). As shown by others (Gessert and Kühl
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Adding to the growing repertoire
2018-11-08
Adding to the growing repertoire of available cardiac injury models for neonatal mice, Jesty et al. recently reported on the cardiomyogenic potential of neonatal mice following cryoinjury (Jesty et al., 2012). In response to cryoinfarction at 1–3days-of-age, neonatal mice underwent a marked cardiomy
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Among six pluripotency regulators examined only NANOG and PO
2018-11-08
Among six pluripotency regulators examined, only NANOG and POU5F1 were downregulated by 2days of LY364947 treatment, which impaired DE competence. NANOG is a direct target of Nodal/Activin signaling, and the maintenance of its expression requires active Nodal/Activin signaling (Xu et al., 2008; Cham
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Runx also controls the proliferation and neuronal differenti
2018-11-08
Runx1 also controls the proliferation and neuronal differentiation of certain neural progenitor cell populations. In embryonic olfactory bulb progenitor cells in vivo, as well as in cultures of either embryonic olfactory progenitor cells or embryonic cortical NSPCs, Runx1 increases cell proliferatio
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However the relative contribution of factors provided
2018-11-08
However, the relative contribution of factors provided by the different niche prostaglandin receptor including the precursor cells themselves, endothelial cells, pericytes, neurons and astrocytes to this concert has not yet been systematically explored for the hippocampus. There are no widely usable
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