• br We sincerely appreciate the comment by Lombardi

  2019-06-15

  

  We sincerely appreciate the comment by Lombardi et al on our published paper. demonstrates the incidence of dyspnea and the discontinuation of ticagrelor due to dyspnea in patients who reported dyspnea in Phase 3/4 clinical trials of acute coronary syndrome with available relevant data. Our study

• br The follow up clinic These trial results have significant

  2019-06-15

  

  The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ

• br Voltage gated sodium channels

  2019-06-15

  

  Voltage-gated sodium domoic acid are essential for modulating the amplitude and upstroke velocity of the cardiac action potential, which are parameters that are important determinants of impulse propagation and conduction velocity through the myocardium. Functional analyses using patch-clamp tech

• The need for better measurement of gender empowerment cannot

  2019-06-15

  

  The need for better measurement of gender empowerment cannot be understated, given that 80% of indicators to monitor SDG5 lack adequate data, often because of an absence of valid measures. Although measures of gender empowerment are available, and more are being developed, there is no consensus on t

• br Raising taxes on tobacco is the measure with the

  2019-06-15

  

  Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2

• br Methods br Results Four

  2019-06-14

  

  Methods Results Four patients withdrew from the study due to elevated liver function, allergy to oxaliplatin, refusal of surgery, and refusal of chemotherapy, respectively. The total number of patients included in the final analysis was 31. The patients’ characteristics are presented in Table

• Introduction Despite advances in the treatment of early stag

  2019-06-14

  

  Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant sodium salt [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidiscipl

• br Conclusion br Conflict of interest

  2019-06-14

  

  Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu

• Long marginalised as a disorder

  2019-06-14

  

  Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th

• inositol phosphatase With the publication of this month

  2019-06-14

  

  With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy inta

• We modelled how the loss of health care workers defined

  2019-06-14

  

  We modelled how the loss of health-care workers—defined here as doctors, nurses, and midwives—to Ebola might affect maternal, infant, and under-5 mortality in Guinea, Liberia, and Sierra Leone, with the aim of characterising the order of magnitude of likely effects, not providing specific prediction

• Having to seek various approvals with no communication betwe

  2019-06-14

  

  Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen

• Assim a decis o de avan ar

  2019-06-14

  

  Assim, papain inhibitor decisão de avançar sobre Lima deve ser entendida antes como uma “fuga para frente” do que como desdobramento de um crescimento orgânico. Mas em seu momento, havia um genuíno receio em relação ao poder insurgente, já que a repercussão das ações senderistas na capital era ampli

• mitotic inhibitors El n mero de que corresponde al segundo s

  2019-06-14

  

  El número 63 de , que corresponde al segundo semestre del presente año 2016, pone mitotic inhibitors disposición de la comunidad académica un conjunto variado de artículos sobre América Latina y un pequeño dedicado a la literatura brasileña. Eduardo Ayala Tafoya abre el número con “Lope de Aguirre:

• Las l neas le comunican a Felipe que

  2019-06-13

  

  Las líneas le comunican 5-fluorocytosine Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Gi

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