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Michel et al calculated the mutual solubilities of water
2019-07-02
Michel et al. [34] calculated the mutual solubilities of water and hydrocarbons by a cubic equation of state. They asserted that conventional mixing rules can not satisfactorily describe the hydrogen bonding compounds. Kabadi and Danner [35] applied a modified form of Soave-Redlich-Kwong equation of
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In humans the ER is
2019-07-02
In humans, the ERα is encoded by the gene ESR1, located on chromosome 6, locus 6q25.1 (Gosden, Middleton, & Rout, 1986). In addition to the full-length ERα isoform (66kDa), several shorter isoforms (36kDa, 46kDa) have been identified as a result of the presence of alternate start codons, or as produ
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br Conflict of interest statement br
2019-07-02
Conflict of interest statement Acknowledgement The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 278742 (Eurosarc) Introduction Pseudomyogenic hemangioendothelioma/epithelioid sarcoma-like
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Taken together these assays demonstrate that SUMOD
2019-07-02
Taken together, these assays demonstrate that SUMOD positioning is essential for all E3 ligases but dispensable for E2 and S*E2 sumoylation reactions. Thus, we propose SUMOD positioning as a key criterion to describe the enzymatic function of SUMO E3 ligases that distinguishes them from other enhanc
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URB597 br Results and Discussion br Experimental Procedures
2019-07-02
Results and Discussion Experimental Procedures Acknowledgments The ubiquitin–proteasome system (UPS) is important for biological processes such as protein degradation and protein function regulation. In general, poly-ubiquitinated proteins are degraded by proteasomes, and some proteins ac
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br Acknowledgments The authors thank Dr Tai Sheng Cheng
2019-07-02
Acknowledgments The authors thank Dr. Tai-Sheng Cheng, Yu-Wen Huang and Ting-Wei Gau for technical assistance. This work was supported by the National Science Council of TaiwanNSC 98-2320-B-024-002-MY3 and National University of TainanAB102-216. This information is available free of charge via th
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br Functional significance Defects of the lysyl
2019-07-01
Functional significance Defects of the lysyl hydroxylases LH1, LH2, and LH3 impair collagen secretion and stability in the extracellular matrix, and cause rare connective tissue disorders such as Ehlers-Danlos type-VI [27], Bruck syndrome [28], and skeletal dysplasia [29], respectively. Elucidati
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The imbalances in the current R D system were the
2019-07-01
The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle
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Pimozide of Even so the purpose of our Comment was
2019-07-01
Even so, the purpose of our Comment was to counter the notion that is useful to think in terms of “Ebola suspects” and their ostensible options, while reminding us to question whether the fetishisation of isolation over treatment was “an institutionalized form of non-assistance” that resulted in “a
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br Material and methods br Results br Discussion This study
2019-07-01
Material and methods Results Discussion This study showed the rate of recurrent of VT/VF in symptomatic Thai BS patients who received ICD pituitary adenylate cyclase-activating peptide as a secondary prevention. After approximately 1.5 years of follow-up, the recurrence of VT/VF in symptom
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Nonaka et al have described that the right diaphragm
2019-07-01
Nonaka et al. have described that the right diaphragm is greatly elevated, the left ventricle tends to move vertically, and the ascending VE-822 moves to the right side after a right upper lobectomy [9]. In this patient, it was unknown whether the right upper lobectomy resulted in the observed desc
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Since many decades bone tumours have stimulated imagination
2019-07-01
Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh
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Moore et al in a study of
2019-07-01
Moore et al., in a study of 40 patients with sarcoidosis and musculoskeletal symptoms, found intramedullary bone lesions on MRI in 43% of patients (17/40) [5]. The lesions ranged in size from 1 to 4cm. Lesions of the large bones and 4 methylumbelliferone of were present in 33% of patients (13/40), 9
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Introduction Schwannoma is a benign tumor of
2019-07-01
Introduction Schwannoma is a benign tumor of neuroectodermal derivation that originates from Schwann Calcium Ionophore I which cover the peripheral nerves [3]. Approximately 25–40% of all schwannomas occur in the head and neck. These tumors most commonly arise in the soft tissues of the head and
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On the other hand several authors reported that an ATP
2019-07-01
On the other hand, several authors reported that an ATP Pyrrolidinedithiocarbamate ammonium of injection could promote significant sympathomimetic effects. Biaggioni et al. suggested that intravenous ATP administration primarily activates afferent nerves via arterial (or carotid body) chemoreceptor
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