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Abnormal expression and higher activity of
2022-02-14

Abnormal expression and higher activity of GLO I have been detected more in various tumor 172 5 australia than in normal cell samples., , , , , , , Among cancer cell lines, lung carcinoma cells frequently showed higher GLO1 activity. Human NSCLC cell line NCI-H522 cells possess high activity and exp
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br Conclusion br Experimental procedures br Introduction The
2022-02-14

Conclusion Experimental procedures Introduction The glycine receptor (GlyR) is a member of the Cys-loop family of ligand-gated ion channels. It is the primary inhibitory receptor in the brainstem and spinal cord but also plays important roles in higher number of moles calculator regions, i
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Growing evidence suggests that the glycine site seems
2022-02-14

Growing evidence suggests that the glycine site seems to play a pivotal role in NMDAR-related function. For example, it survivin (baculoviral IAP repeat-containing protein 5) (21-28) has been demonstrated in a hippocampal slice study that the glycine site sub-serves the spatiotemporal detection of
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Nano SiO was a kind of versatile material for enzyme
2022-02-14

Nano-SiO2 was a kind of versatile material for enzyme immobilization because of its excellent properties, including low cost, lack of toxicity, high stability, large specific surface area and high biocompatibility [10]. After the immobilization on nano-SiO2, the selectivity of enzymatic reactions wo
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br Conflict of interest statement br Introduction br Gap jun
2022-02-14

Conflict of interest statement Introduction Gap junction assembly Induced disassembly of gap junctions The regulation of connexin and gap junction turnover are still not well understood. This is, in part, due to the fact that while the overall turnover of connexin molecules is fairly con
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Akt mTOR signaling pathway is a major negative regulator
2022-02-14

Akt/mTOR signaling pathway is a major negative regulator of autophagy, via modulating ULK1 complex. It is well established that Inhibition of mTOR by deprivation of nutrients or growth factors, led to dephosphorylation of ULK1, ULK2, and Atg13 in human cells, which is a key step for ULK1 complex ass
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2 deoxy d glucose br Development of calibrators and
2022-02-14

Development of calibrators and controls for DiXaIs Method validation and comparison with reference technique (LC:MS) At this stage, anti-Factor Xa bioassays can be established for reliably measuring DiXaI concentrations in plasma, with the available appropriate drug specific calibrators and co
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br Introduction Erythropoietin EPO is a
2022-02-12

Introduction Erythropoietin (EPO) is a glycoprotein hormone and the principal stimulator of erythropoiesis (Jelkmann, 2011). EPO promotes the proliferation and differentiation of red blood cells, which is important for oxygen transport. Low EPO levels in blood cause anemia; however, excessive lev
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OS has a key role in the pathogenesis
2022-02-12

OS has a key role in the pathogenesis of micro- and macrovascular diabetic complications [3]. There is now convincing evidence that the enzymes that generate ROS and gasotransmitters, such as nitric oxide (NO) and CO, are redox regulated at both the transcription and activity levels, and are also im
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Corollary and Lemma Finally Corollary and
2022-02-12

(Corollary 3 and Lemma 9). Finally, Corollary 5 and Lemma 10 show that if then the support of is wide enough and so must contain the points of maximum of the attached. However, the support of is too narrow and so does not contain the points of maximum of the remote. Hence, the remote has at most two
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Based on the role of NMDA
2022-02-12

Based on the role of NMDA receptors in initiation and propagation of epileptic seizures and on potentiation of NMDA function by glycine, it has been hypothesized that glycine will have proconvulsant activity (Foster and Kemp, 1989). Indeed, there is some evidence that human epileptogenic foci, remov
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In this study we provide biochemical and immunohistochemical
2022-02-12

In this study we provide biochemical and immunohistochemical evidence for the localization of the glycine transporter GLYT1 in synaptic vesicles. Previously, it was thought that GLYT1 was exclusively a glial protein (Zafra et al., 1995a). However, due to a partial discrepancy between mRNA and protei
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br Introduction Cherry tomato Solanum lycopersicum L is
2022-02-12

Introduction Cherry tomato (Solanum lycopersicum L.) is a commonly consumed fruit on a worldwide scale due to its characteristic flavor and high nutrition (Wei et al., 2016, Yu et al., 2014). Tomato is low in fat and calories, and is a rich natural source of nutrition and bioactive antioxidant co
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Besides its established insulinotropic actions GIP has been
2022-02-12

Besides its established insulinotropic actions, GIP has been shown to possess other direct beneficial effects on the beta cell, including stimulation of growth, differentiation, proliferation and survival.21, 22, 23 It has also been shown to stimulate proinsulin gene transcription and translation. M
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Despite a robust impact on learned social feeding behaviors
2022-02-12

Despite a robust impact on learned, social feeding behaviors, we observed no differences in body weight or food intake when the control or vHP GHSR-1A KD animals were maintained on either a normal chow diet or a Western diet high in fat and sugar. This is interesting in light of our previous work sh
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