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sodium fluoride receptor The ORR obtained with crizotinib o
2024-12-20
The ORR obtained with crizotinib on our cohort was low compared to other studies, such as the prospective studies of A. Shaw et al. (ORR = 65% in second line), B. Solomon et al. (ORR = 74% in first line) and the more comparable large retrospective study of M. Duruisseaux et al. on the French CLINALK
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Oxamic acid br Materials and methods br Results br Discussio
2024-12-20
Materials and methods Results Discussion Competing financial interests Acknowledgements The work was partially supported by grants from the National Natural Science Foundation of China (Grant no. 31530053 and 31401424) and National Science and Technology Support Plan (Grant no. 2013BA
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This study revealed that EAAT
2024-12-20
This study revealed that EAAT2 cerdulatinib was increased 4–8 weeks after cauterization as our previous work (Park et al., 2009). RGC death could not be blocked despite activation of EAAT2, which is one of glutamate transporters in cone photoreceptors and some bipolar cells, in chronic ocular hyper
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In recent years there have been further significant developm
2024-12-20
In recent years, there have been further significant developments that enhance an understanding of the role of adenosine in nociception. Thus, novel methods of recruiting adenosine A1Rs have been developed, and the role of adenosine A2A- and A3Rs in nociception has been further elaborated. Furthermo
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In recent years there have been further significant developm
2024-12-20
In recent years, there have been further significant developments that enhance an understanding of the role of adenosine in nociception. Thus, novel methods of recruiting adenosine A1Rs have been developed, and the role of adenosine A2A- and A3Rs in nociception has been further elaborated. Furthermo
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br Results br Discussion Today enzymes play important
2024-12-20
Results Discussion Today, enzymes play important roles in various fields. A good assay for enzyme activity is of great value, especially when it has good specificity, sensitivity, reproducibility and economy. ADK is the first identified enzyme in the metabolic pathway of adenosine salvage [15,
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5153 We also investigated the transmittance of actin
2024-12-20
We also investigated the transmittance of actin polymerized with and without ABP. The presence of actin in the solution results in an increment in turbidity as other proteins provided 5153 features [21], [32]. While G-actin showed a transmittance peak positioned at 241 nm, F-actin exhibited a small
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br Difference between ACh and ER tests There are few
2024-12-19
Difference between ACh and ER tests There are few reports concerning the provoked spasm between ER and ACh in the same patients [51], [52], [53]. Different mediators may have the potential of different coronary responses. In our experience, spasm provoked by intracoronary injection of ER is focal
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br Conflict of interest statement br Benign prostatic hyperp
2024-12-19
Conflict of interest statement Benign prostatic hyperplasia (BPH) is a highly complex process characterized by an increased number of epithelial and stromal L-α-Aminoadipic Acid in the transition zone. , , Autopsy studies by McNeal detail the evolution of histological changes within these 2 c
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BTL105 Optimization of the B ring specifically targeted prev
2024-12-19
Optimization of the B-ring specifically targeted preventing the oxidation of the ring system (). As described above, the 4-position of the phenyl ring provides the appropriate vector towards bulk solvent. - and -linked substitutions at the 4-position of the B-ring from the 4-fluoro-nitrophenyl inter
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br Concluding Remarks and Future Directions The physiologica
2024-12-19
Concluding Remarks and Future Directions The physiological significance of autophagy in neuronal function is steadily emerging. The studies discussed herein reveal that key neuronal functions, such as neurotransmitter release, pruning of dendritic spines, and behavioural outputs of neural network
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edu assay In the last decade the
2024-12-19
In the last decade, the zebrafish has emerged as a valuable vertebrate model to systematically dissect the genetic underpinnings of both vertebrate heart development and function [8,9], as well as distinct cardiac diseases such as congenital heart disease [10], cardiomyopathies [11,12] and cardiac a
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In this study we observed the ATPase activity of
2024-12-19
In this study, we observed the ATPase activity of RaGroEL at various temperatures and metal ions conditions and the role of GroES in the ATPase activity of RaGroEL. Furthermore, we quantified the expression of groEL genes under different abiotic stresses, including temperature, pH, salt and oxygen s
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It was reported that overexpression of the
2024-12-19
It was reported that overexpression of the rat ACL gene in tobacco increased the total ACL activity by 4 fold, which increased the production of fatty acids by 16% [8]. Recently, a 1.7-fold increase of fatty acids and 1.9-fold increase of triacylglycerol (TAG) was observed in Aspergillus oryzae with
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We further evaluated the possibility whether letrozole media
2024-12-19
We further evaluated the possibility whether letrozole mediates its effect through diverting the pathway towards 5α-DHT and further to 3α-Diol. For this purpose, we measured the concentrations of 5α-DHT and 3α-Diol in mice hippocampus and found that letrozole elevated both 5α-DHT and 3α-Diol levels
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