• During the ACh provocation test our patient did not

  2019-06-21

  

  During the ACh provocation test, our patient did not complain of chest pain, ECG showed no discernible ST-T changes, and CAG demonstrated no spastic findings. These indicate that ACh evoked the J wave by its direct pharmacological actions in this case. J waves are currently recognized as a surface E

• Well designed operational research is needed to refine

  2019-06-21

  

  Well designed operational research is needed to refine this starting point. Research is also needed to find out whether prophylactic valganciclovir treatment in high-risk patients might reduce AIDS mortality as well as blindness, as substantial data suggest. WHO leadership is needed to provide cytom

• Assessment of the growth of children is fundamental to

  2019-06-21

  

  Assessment of the growth of children is fundamental to paediatrics. Aberrations of growth, whether too little or too much, can be signs of current or past ill health, particularly in the case of poor growth, or portend later ill health, particularly with excessive weight gain. To know whether growth

• In Fatima Mir and colleagues report results from the Simplif

  2019-06-20

  

  In , Fatima Mir and colleagues report results from the Simplified Antibiotic Therapy Trial (SATT) in Pakistan, in which three antibiotic regimens were compared for treatment of neonatal infections: procaine benzylpenicillin and gentamicin; amoxicillin and gentamicin; and procaine benzylpenicillin, g

• The standard therapy for chordoma is excision Local recurren

  2019-06-20

  

  The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c

• Introduction Dabigatran Boehringer Ingelheim Ingelheim Germa

  2019-06-20

  

  Introduction Dabigatran (Boehringer Ingelheim, Ingelheim, Germany) is a direct thrombin inhibitor, which can be orally administered, and is used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). In early phase studies of dabigatran in healthy men, TKI

• br Por su parte Pietro

  2019-06-20

  

  Por su parte, Pietro Cerone tiene algunos pasajes, como el titulado “Del neuma usado en cantollano”, donde considera el carácter espiritual de la música. Tomando el concepto de Gaffurio sobre el neuma como voz de una sola respiración, asevera: Añade un comentario sobre el mismo tema en el que enc

• br Results We evaluated MM

  2019-06-20

  

  Results We evaluated 148 MM patients, 87 women and 61 men, age range 29–69 years, 58 of whom developed bacteremia during the early post-transplant period (Table 1). The genotypes were in Hardy–Weinberg equilibrium. We did not observe any statistically significant association between the genotypes

• Amiodarone has been used in Japan for more than

  2019-06-20

  

  Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter

• br Historical overview Before the development of

  2019-06-20

  

  Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the CGP 53353 muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a major conce

• This trial included patients who met the ICD criteria

  2019-06-20

  

  This trial included 1500 patients, who met the ICD criteria for primary prevention (non-ischemic, ischemic, dual chamber ICD or CRT-D). The patients were randomized to 3 arms: (1) conventional therapy: Zone 1(VT) 170bpm, 2.5s delay, Zone 2 (VF) 200bpm, 1s delay; (2) high rate therapy: Zone 1(VT) 170

• The main products of EBM are evidence based

  2019-06-20

  

  The main products of EBM are evidence-based guidelines (EBGs), “systematically developed statements to assist practitioner and patient decision about appropriate health care for specific clinical circumstances” [21]. EBGs indeed substantially improve clinical care [29]. Preliminary steps for guidel

• br Conclusion br Conflict of interest statement

  2019-06-20

  

  Conclusion Conflict of interest statement Authors\' contribution Introduction There are two classes of bisphosphonates that differ with regard to structure and mechanism of action [1]. The first one includes pyrophosphate-resembling bisphosphonates, such as clodronate and etidronate, whi

• Preclinical studies have shown that

  2019-06-20

  

  Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer pyruvate dehydrogenase kinase inhibitor [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- ind

• Worldwide there are an estimated specialist

  2019-06-20

  

  Worldwide, there are an estimated 1 112 727 specialist surgeons (IQR 1 059 158–1 177 912), 550 134 anaesthesiologists (529 008–572 916) and 483 357 obstetricians (456 093–517 638; ). Low-income and lower-middle-income countries, representing 48% of the global population, have 20% of this workforce,

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