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Rabies has no cure and by the time of
2019-06-17

Rabies has no cure, and by the time of clinical onset it is invariably fatal. More than 95% of deaths occur in Africa and Asia, 80% of which are in people living in rural, underserved populations, most of whom are children. Community awareness about the power of preventing dog bites and of life-savi
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br Conflict of interest br Introduction
2019-06-17

Conflict of interest Introduction Idiopathic left ventricular tachycardia (ILVT) with a right bundle-branch block (RBBB) configuration and superior or left axis is a distinct entity that arises in the left ventricle, mostly because of a reentry mechanism and is usually verapamil sensitive [1–6
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Table shows the results of achieving
2019-06-17

Table 3 shows the results of achieving ECV for atrial arrhythmia in this study. There was no significant between-group difference in the number of ECV attempts or the prevalence of successful ECV. The number of days to ECV in OAC-naïve patients was significantly less in the NOACs group (n=72) compar
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br Genetic basis for atrial standstill
2019-06-15

Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins a
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br We sincerely appreciate the comment by Lombardi
2019-06-15

We sincerely appreciate the comment by Lombardi et al on our published paper. demonstrates the incidence of dyspnea and the discontinuation of ticagrelor due to dyspnea in patients who reported dyspnea in Phase 3/4 clinical trials of acute coronary syndrome with available relevant data. Our study
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br The follow up clinic These trial results have significant
2019-06-15

The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ
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br Voltage gated sodium channels
2019-06-15

Voltage-gated sodium domoic acid are essential for modulating the amplitude and upstroke velocity of the cardiac action potential, which are parameters that are important determinants of impulse propagation and conduction velocity through the myocardium. Functional analyses using patch-clamp tech
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The need for better measurement of gender empowerment cannot
2019-06-15

The need for better measurement of gender empowerment cannot be understated, given that 80% of indicators to monitor SDG5 lack adequate data, often because of an absence of valid measures. Although measures of gender empowerment are available, and more are being developed, there is no consensus on t
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br Raising taxes on tobacco is the measure with the
2019-06-15

Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2
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br Methods br Results Four
2019-06-14

Methods Results Four patients withdrew from the study due to elevated liver function, allergy to oxaliplatin, refusal of surgery, and refusal of chemotherapy, respectively. The total number of patients included in the final analysis was 31. The patients’ characteristics are presented in Table
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Introduction Despite advances in the treatment of early stag
2019-06-14

Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant sodium salt [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidiscipl
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br Conclusion br Conflict of interest
2019-06-14

Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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Long marginalised as a disorder
2019-06-14

Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th
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inositol phosphatase With the publication of this month
2019-06-14

With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy inta
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We modelled how the loss of health care workers defined
2019-06-14

We modelled how the loss of health-care workers—defined here as doctors, nurses, and midwives—to Ebola might affect maternal, infant, and under-5 mortality in Guinea, Liberia, and Sierra Leone, with the aim of characterising the order of magnitude of likely effects, not providing specific prediction
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