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In silico prediction software SIFT PolyPhen CADD
2019-06-25

In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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The exact location of the APs within the
2019-06-25

The exact location of the APs within the cusps is difficult to determine. The majority of studies used coronary angiography, and less commonly electroanatomical mapping. The morphology of local atrial and ventricular electrograms may be additionally used [1,2]. Mapping within the RCC typically shows
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It is good to see
2019-06-25

It is good to see any cluster-randomised dhfr inhibitors trial of a handwashing intervention, much more a successful one. Globally there is considerable funding invested in handwashing promotion, yet the kind of rigorous study published in this month\'s issue of by Adam Biran and colleagues is rar
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Entre los cronistas y sin
2019-06-25

Entre los cronistas, y sin dejar atrás esta concepción de la naturaleza y sin que se perciba un mayor conflicto, se advierte, en mayor o menor medida, un acentuado interés por los seres naturales y las “causas segundas”. La razón de esta falta de conflicto frontal obedece, por un lado, al reconocimi
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Conflicts of interest br Introduction Hepatocellular
2019-06-25

Conflicts of interest Introduction Hepatocellular carcinoma (HCC) is one of the most common cancers and is the second leading cause of cancer death worldwide. In 2012, 782,500 new HCC cases and 745,500 deaths were caused by this persistent disease worldwide, with about 50% of the total number of
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Curiosamente las dos obras que pueden considerarse germinale
2019-06-24

Curiosamente, las dos obras que pueden considerarse germinales del pensamiento complejo, tales como Ciencia con consciencia e Introducción al pensamiento complejo, son obras de recopilación de trabajos dispersos, aunque ramificados lógicamente. Antes que tratados sistemáticos y elaborados desde el
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Una de las teor as m s
2019-06-24

Una de las teorías más destacadas sobre el género lo emparenta con el proyecto que llevaron SU11274 of cabo autores alemanes como Bertold Brecht o Walter Benjamin, quienes: Ana María Amar Sánchez, teórica que propone esta línea genealógica para explicar la creación testimonial del argentino Rodolfo
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A facility survey from reported
2019-06-24

A facility survey from 2003 reported that NSC 652287 only 15% of primary health centres provided abortion services. Another study from Rajasthan state revealed that nine districts included 83% of all facilities whereas the remaining 22 districts included only 17%. Within districts too, abortion fac
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Data continue to show increasing numbers of facility based d
2019-06-24

Data continue to show increasing numbers of facility-based deliveries with an appreciable decline in both maternal and newborn baby deaths. With nearly half of all births being delivered in low volume, primary health facilities, these facilities clearly fulfill a very crucial role in ensuring that p
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Major outcomes from MADIT II trial
2019-06-24

Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co
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NB-598 Maleate structure The majority of breast malignancies
2019-06-24

The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmen
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br Disclosures and funding sources br Conflicts of
2019-06-24

Disclosures and funding sources Conflicts of interest Introduction In 1994, Leenhardt et al. first described electrocardiogram (ECG) findings of torsades de pointes and QT prolongation in patients without demonstrable structural HG-10-102-01 what disease, with the torsades de pointes initi
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T wave was similar in seven
2019-06-24

T-wave was similar in seven patients. The terminal portion of the T-wave was negatively inverted compared with that at baseline in five patients on using ER-2000®. Representative example of sinus rhythm with T-wave discordance is shown in online Supplementary Fig. S3. T-wave morphology was different
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HATU structure br Material and methods br Results
2019-06-24

Material and methods Results Discussion Conclusions Conflict of interest Introduction Scoliosis forms a complex curve in all three planes, not only in the coronal plane, leading to deformities caused by the self-rotating movement of the spine [1]. Spinal anomalies may impair cardio
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PROFACE aimed to investigate the
2019-06-24

PROFACE aimed to investigate the efficacy of atorvastatin in preventing POAF and SIRS. Atorvastatin, 40mg/day, was administered 7 days before and after elective NVP-LCQ195 of valve surgery in a randomized patient population with no preoperative beta-blocker treatment or previous episodes of AF. The
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