• Rationale Anterior cervical discectomy and fusion ACDF has b

  2018-11-12

  

  Rationale Anterior cervical discectomy and fusion (ACDF) has been accepted as the gold standard of surgical management for cervical spondylosis and disc disease causing radiculopathy or myelopathy. High patient-satisfaction scores and high arthrodesis rates associated with ACDF have been reported i

• Enophthalmos is a common sign of

  2018-11-12

  

  Enophthalmos is a common sign of orbital fracture. Enophthalmos ≥2 mm is aesthetically unacceptable and requires surgical correction. The severity of enophthalmos and treatment outcome following surgery are related to the number, location, and size of orbital wall fractures. Raskin et al reported th

• Most recently it has been demonstrated that sclerotial gluca

  2018-11-12

  

  Most recently, it has been demonstrated that sclerotial β-glucans can be utilized by human colonic bacteria in vitro and therefore they have the potential to be used as novel prebiotics that can influence human gut health by selectively modulating the growth of probiotic bacteria including bifidobac

• br Materials and methods br

  2018-11-12

  

  Materials and methods Results and discussion Conclusion This study revealed that aqueous and methanol extracts from H. crinita leaves modulates the activities of btk inhibitor (MOA, AChE, BChE and Na+/K+-ATPase) linked to neurodegenerative diseases, as well as inhibit Fe2+-induced lipid pe

• br Integrin Expression in Human Stem Cells Integrin expressi

  2018-11-12

  

  Integrin Expression in Human Stem Cells Integrin expression in human embryonic stem JNJ-26481585 and selected adult stem cell types is summarised in Table 2. We define here the known expression profiles of integrins on human stem cells of four different types: embryonic, mesenchymal, haematopoie

• Many immunity associated genes previously linked

  2018-11-12

  

  Many immunity-associated genes previously linked to MSCs were also expressed by all 3 cell populations, particularly by bmMSC. A comparison of the functional capacity of each population to influence lymphocytic proliferation suggested significant differences between the three sources of cells, with

• In mice Oct encodes at least

  2018-11-12

  

  In mice, Oct4 encodes at least 2 variants, designated Oct4A and putative Oct4B. Oct4A was detected in somatic stem cells and has been recognized as a gatekeeper for maintaining pluripotency in embryonic stem cells and pre-implantation embryos. However, because of the existence of pseudogene and misi

• Although WNT A in isolation

  2018-11-12

  

  Although WNT3A in isolation was a poor mesoderm inducer in hESCs differentiated in APEL medium, it synergized with BMP4 to efficiently induce MIXL1-GFP+ mesoderm, increasing the yield of Bl-CFCs and hematopoietic CFCs. Our data complement studies in which specific roles for BMP and WNT signaling dur

• br Introduction Stem cell divisions resulting in alternative

  2018-11-12

  

  Introduction Stem cell divisions resulting in alternative pathways of self-renewal or differentiation require very distinctive epigenetic regulation of gene expression from the same genome. Where division has a symmetrical output of progeny cells, the assumption is that the molecular signatures d

• Here we report that Dll counteracts the proliferation of mur

  2018-11-12

  

  Here we report that Dll4 counteracts the proliferation of murine HPCs such as Lin−Sca+c-Kit+ (LSK) cells, by keeping a higher fraction of cells in the G0 state. This event was correlated with a downmodulation of some key herpes simplex virus 1 genes transcription such as D-CYCLINS. Furthermore, Dll

• Recapitulating developmental signaling pathways in different

  2018-11-12

  

  Recapitulating developmental signaling pathways in differentiated cardiomyocytes has the potential to stimulate proliferation. Under this premise, developmental signaling pathways should be present in differentiated cardiomyocytes and available for activation. For example, developmentally expressed

• Placental growth factor PlGF is

  2018-11-12

  

  Placental growth factor (PlGF) is an angiogenic protein often highly upregulated in solid tumors contributing to their growth and survival (Kim et al., 2012). PlGF can promote angiogenesis either by directly stimulating endothelial cell growth or by recruiting pro-angiogenic cell types. Of the two m

• br Materials and methods br Author disclosure statement br

  2018-11-12

  

  Materials and methods Author disclosure statement Acknowledgments We are grateful to Prof. Angel Raya for his help and advice with iPS cell generation. This work was supported by grants from the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER) (grant 13-717/132.05

• From previous studies we know that cells above

  2018-11-09

  

  From previous studies we know that cells above the bulge that are Sca-1 and CD34 negative also possess stem cell properties and that these stem cells are not label retaining cells, but relatively active in actin polymerization inhibitor (Jensen et al., 2008). This suggests that LRCs primarily refle

• It has previously been reported

  2018-11-09

  

  It has previously been reported that differentiation of hESCs without the embryonic body stage led to an increase in the capacity of hESCs to differentiate into osteogenic progenitor Torin1 (Karp et al., 2006). Consistent with these findings, our differentiation culture method resulted in cells with

15515 records 1014/1035 page Previous Next First page 上5页 10111012101310141015 下5页 Last page